Molecular weight is a game changer, influencing hyaluronic acid properties. In fact, high molecular weight hyaluronic acid (> 1.000kDa) is more similar to human hyaluronic acid (6.000kDa) compared to low molecular weight one leading to more benefits for skin and joints.
Improved lubrication: high molecular weight hyaluronic acid is more effective than Low molecular weight hyaluronic acid in increasing the viscosity of synovial fluid, leading to improved lubrication and reduced friction within the joints.
Anti-inflammatory properties: Several studies suggest High molecular weight hyaluronic acid possesses superior anti-inflammatory properties than low molecular weight one, being also more effective in stimulating the production of aggrecan, a key component of healthy cartilage and better supporting chondrocytes proliferation.
Wound healing: High molecular weight hyaluronic acid surpasses low molecular weight one in promoting wound healing. It activates genes crucial for cell growth, movement, and matrix formation, while suppressing inflammatory genes.
Hydration and protection: high molecular weight hyaluronic acid creates a film on the skin, acting as a long-lasting moisture barrier compared to low molecular weight one, which degrades faster.
